I was awarded my PhD in 2008 from the University of London. I then undertook post doctoral research at Pfizer in Sandwich, Kent in the bioinformatics department seconded to the anti-viral research unit. I am currently in the epigenetics group of Neusentis in Cambridge, UK. I'm interested in all things cool in molecular biology, epigenetics, bioinformatics and where they cross over. You can find me on twitter and can check out my #coolscience blog at sidderb.posterous.com
An Integrated Transcriptomic and Meta-Analysis of Hepatoma Cells Reveals Factors That Influence Susceptibility to HCV Infection.
MacPherson JI, Sidders B, Wieland S, Zhong J, Targett-Adams P, Lohmann V, Backes P, Delpuech-Adams O, Chisari F, Lewis M, Parkinson T and Robertson DL.
PLoS ONE. 2011. 6(10): e25584.
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Causal Reasoning on Biological Networks: Interpreting Transcriptional Changes.
Chindelevitch L, Ziemek D, Enayetallah A, Randhawa R, Sidders B, Brockel C and Huang E.
Lecture Notes in Computer Science; Research in Computational Molecular Biology, Springer. 2011. ISBN: 978-3-642-20035-9. DOI: 10.1007/978-3-642-20036-6 4.
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Selection, optimization, and pharmacokinetic properties of a novel, potent antiviral locked nucleic Acid-based antisense oligomer targeting hepatitis C virus internal ribosome entry site.
Laxton C, Brady K, Moschos S, Turnpenny P, Rawal J, Pryde DC, Sidders B, Corbau R, Pickford C and Murray EJ.
Antimicrob Agents Chemother. 2011. 55(7): 3105-14.
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Screening highly expressed mycobacterial genes identifies Rv3615c as a useful differential diagnostic antigen for the Mycobacterium tuberculosis complex.
Sidders B, Pirson C, Hogarth PJ, Hewinson RG, Stoker NG, Vordermeier HM and Ewer K.
Infection and Immunity. 2008. 76(9): 3932-9.
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Mycobacterium tuberculosis strains disrupted in mce3 and mce4 operons are attenuated in mice.
Senaratne R, Sidders B, Sequeira P, Saunders G, Dunphy K, Marjanovic O, Reader J.R, Lima P, Chan S, Kendall S, McFadden J and Riley L.W.
J. Med. Microbiology. 2008. 57: 164-170.
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Quantification of global transcription patterns in prokaryotes using spotted microarrays.
Sidders B, Withers M, Kendall SL, Bacon J, Waddell SJ, Hinds J, Golby P, Movahedzadeh F, Cox RA, Frita R, ten Bokum AMC, Wernisch L and Stoker NG.
Genome Biology. 2007. 8(12): R265.
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A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis.
Kendall SL, Withers M, Soffair CN, Moreland NJ, Gurcha S, Sidders B, Frita R, Ten Bokum A, Lott S, Besra GS and Stoker NG.
Mol. Microbiology. 2007. 65(3): 684-699.
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Enhanced mortality despite control of lung infection in mice aerogenically infected with a Mycobacterium tuberculosis mce1 operon mutant
Lima P, Sidders B, Morici L, Reader R, Senaratne R, Casali N and Riley LW.
Microbes and Infection. 2007. 9(11): 1285-1290.
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Mycobacteria: Biology.
Sidders B and Stoker N. 2007.
Encyclopedia of Life Sciences (ELS). John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/9780470015902.a0020389.
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Transcriptome Analysis: Towards a Comprehensive Understanding of Global Transcription Activity.
Sidders B and Stoker N. 2006.
Chapter in: Pathogenomics: Genome Analysis of Pathogenic Microbes, Edited by Hacker J and Dobrindt U. Published by Wiley-VCH. ISBN: 3-527-31265-X.
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5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice.
Senaratne RH, De Silva AD, Williams SJ, Mougous JD, Reader JR, Zhang T, Chan S, Sidders B, Lee DH, Chan J, Bertozzi CR, Riley LW.
Mol Microbiol. 2006 59(6):1744-53.
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Hypervirulent mutant of Mycobacterium tuberculosis resulting from disruption of the mce1 operon.
Shimono N, Morici L, Casali N, Cantrell S, Sidders B, Ehrt S, Riley LW.
Proc Natl Acad Sci U S A. 2003 100(26):15918-23.
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